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Infant study casts doubt on vaccine-autism link |
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Written by Maggie Fox, Health and Science Editor
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Thursday, 31 January 2008 |
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WASHINGTON, Jan 30 (Reuters) - The mercury in a vaccine preservative is
pumped out of a baby's body too quickly for it to do any damage,
researchers reported on Wednesday in a study they say should further
absolve shots of causing autism.
The study in the journal
Pediatrics reinforces what many vaccine experts have said for years --
that the form of mercury found in the preservative is handled
differently by the body than the kind found in pollution and
contaminated fish.
"It takes a certain amount of time and a
certain concentration ... to make it into the brain," Dr. Michael
Pichichero of the University of Rochester in New York, who led the
study, said in a telephone interview.
Thimerosal is widely used
to preserve vaccines and is made from a kind of mercury called ethyl
mercury. It allows vaccines to be distributed in multi-dose containers.
"The World Health Organization has continued to sanction the use of
thimerosal in vaccines because it has proven to save many lives by
preventing bacterial contamination," said Pichichero, who has served as
a consultant to several vaccine manufacturers and the WHO.
Many
studies have shown thimerosal is safe, but some vocal groups have
continued to lobby against its use and it has been removed from all
childhood vaccines in the United States except for some influenza
vaccines.
Pichichero's team studied 216 infants from R.
Gutierrez Children's Hospital in Buenos Aires, Argentina, where
thimerosal is still routinely used in vaccines.
They were
divided into three age groups to have their blood-mercury levels tested
before and after they were immunized at their newborn, 2- or 6-month
checkups.
Blood tests showed the half-life of ethyl mercury --
the time it takes for the body to dispose of half of it -- was 3.7
days. The more dangerous methyl mercury, known to damage nerves, has a
half-life of 44 days.
GONE TOO FAST
"Until recently,
that longer half-life was assumed to be the rule for both types of
mercury," Pichichero said. "Now it's obvious that ethyl mercury's short
half-life prevents toxic build-up from occurring. It's just gone too
fast."
The blood tests also showed most of the infants had
methyl mercury in their blood, at safe levels, before they were ever
vaccinated, he said.
Autism is marked by a variety of
difficulties in social interaction and behavior, from the awkwardness
of Asperger syndrome to severely debilitating repetitive behaviors and
an inability to speak.
The U.S. Centers for Disease Control and
Prevention estimates that one in 150 children has autism or a related
disorder in the United States.
Experts know genes play an
important role. Because autism is often diagnosed in toddlers, who also
have undergone a battery of childhood immunizations, some advocacy
groups argue that the vaccines may have caused the condition.
The U.S. Institute of Medicine reported in 2004 that no link could be
found between vaccines and autism and took the unusual step of urging
researchers to look elsewhere for a cause.
The U.S. debate was
renewed because ABC television is planning to debut a new legal drama
this week with an episode in which a jury finds that a mercury-based
preservative in a vaccine caused a child's autism.
The American Academy of Pediatrics asked ABC to cancel the show but the network has refused.
In a separate study on Wednesday, a team at the University of
Washington's Autism Center reported that children with autism have
normal-size heads at birth but develop accelerated head growth between
six and nine months of age. (Editing by Will Dunham and John
O'Callaghan)
http://www.reuters.com/article/latestCrisis/idUSN30505454
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